• Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly25-Thr305(HLA-A*33:03), Ile21-Met119(B2M) and HVKITDFGR peptide
Catalog #MHC-HM471B
Price
Regular price $341.00
Regular price Sale price $341.00
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Human HLA-A*33:03&B2M&EGFR L858R (HVKITDFGR) Monomer Protein (MHC-HM471B) Summary

Product Description

 Recombinant Biotinylated Human HLA-A*33:03&B2M&EGFR L858R (HVKITDFGR) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*33:03), Ile21-Met119(B2M) and HVKITDFGR peptide.

Product Background

 The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.

Product Category

 Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs | ADC targets

HLA-A*33:03&B2M&EGFR L858R (HVKITDFGR) Specifications

Protein
 HLA-A*33:03&B2M&EGFR L858R (HVKITDFGR)
Synonyms
 ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2

MHC Form

 Monomer

Allele

 HLA-A*33:03
Accession
Species
 Human
Biotinylated
 yes
Amino Acid Range
 Gly25-Thr305(HLA-A*33:03), Ile21-Met119(B2M) and HVKITDFGR peptide
Molecular Weight
 The protein has a predicted MW of 50.8 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi

Fluorophore

 Biotin-labeled
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Biotinylated Human HLA-A*33:03&B2M&EGFR L858R (HVKITDFGR) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human HLA-A*33:03&B2M&EGFR L858R (HVKITDFGR) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human HLA-A*33:03&B2M&EGFR L858R (HVKITDFGR) Monomer is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human HLA-A*33:03&B2M&EGFR L858R (HVKITDFGR) Monomer is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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