Name: Biotinylated Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein (MHC-HM469B)
Brand: KactusBio
SKU: MHC-HM469B-100UG
Availability: InStock

Biotinylated Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein (MHC-HM469B)

Biotinylated Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Monomer is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Amino Acid Range: Gly25-Val309(HLA-B*07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide

Catalog #MHC-HM469B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human HLA-B07:02&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gly25-Val309(HLA-B07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide.
Product Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Product Category	Recombinant Protein / Antibody discovery / MHC

Protein	HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Monomer
Synonyms	MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
MHC Form	Monomer
Allele	HLA-B*07:02
Accession	P01889(HLA-B*07:02)&P61769(B2M)&GADGVGKSAL
Species	Human
Biotinylated	yes
Amino Acid Range	Gly25-Val309(HLA-B*07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide
Molecular Weight	The protein has a predicted MW of 50.40 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20mM PB, 450mM NaCl (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Biotinylated Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Monomer is greater than 95% as determined by SEC-HPLC.