Name: Biotinylated Human IL-17R alpha/CD217 Protein (ILR-HM417B)
Brand: KactusBio
SKU: ILR-HM417B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human IL-17R alpha/CD217 Protein (ILR-HM417B)

ELISA binding curve showing interaction between biotinylated human IL-17R alpha and human IL-17A in a dose-dependent manner.

Immobilized Human IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17R alpha, His Tag with the EC50 of 29.9ng/ml determined by ELISA (QC Test).

Immobilized Human IL-17A&F, His Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17R alpha, His-Avi Tag with the EC50 of 0.21ug/ml determined by ELISA.

Biotinylated Human IL-17R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human IL-17R alpha is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17R alpha, His Tag with the EC50 of 29.9ng/ml determined by ELISA (QC Test).
Amino Acid Range: Leu33-Trp320
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Catalog #ILR-HM417B

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Biotinylated Human IL-17R alpha/CD217 Protein (ILR-HM417B) Summary

Product Description	Recombinant Biotinylated Human IL-17R alpha/CD217 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu33-Trp320.
Product Background	Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Biotinylated Human IL-17R alpha/CD217 Protein (ILR-HM417B) Specifications/Details

Protein	IL-17R alpha/CD217
Synonyms	CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-17R; IL-17R-alpha; IL17Rα
Accession	Q96F46-1
Species	Human
Biotinylated	yes
Amino Acid Range	Leu33-Trp320
Molecular Weight	The protein has a predicted MW of 36.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17R alpha, His Tag with the EC50 of 29.9ng/ml determined by ELISA (QC Test).
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17R alpha, His Tag with the EC50 of 29.9ng/ml determined by ELISA (QC Test).
	Immobilized Human IL-17A&F, His Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17R alpha, His-Avi Tag with the EC50 of 0.21ug/ml determined by ELISA.
	Biotinylated Human IL-17R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human IL-17R alpha is greater than 95% as determined by SEC-HPLC.