Name: Biotinylated Human IL-18BP Protein (IL8-HM4BPB)
Brand: KactusBio
SKU: IL8-HM4BPB-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human IL-18BP Protein (IL8-HM4BPB)

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: The affinity constant of 0.90 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Thr31-Gly194

Catalog #IL8-HM4BPB

Size

100UG

500UG

Order now, ships by:

[{"id":42618368098526,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"IL8-HM4BPB-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human IL-18BP Protein (IL8-HM4BPB) - 100UG","public_title":"100UG","options":["100UG"],"price":52500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584241729758,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"IL8-HM4BPB-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human IL-18BP Protein (IL8-HM4BPB) - 500UG","public_title":"500UG","options":["500UG"],"price":175000,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Biotinylated Human IL-18BP Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Thr31-Gly194.
Product Background	Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
Product Category	Recombinant Protein

Target	IL-18BP
Synonyms	IL-18BP; Igifbp; IL-18BPA
Accession	O95998-2
Species	Human
Biotinylated	yes
Amino Acid Range	Thr31-Gly194
Molecular Weight	The protein has a predicted MW of 20.5 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.90 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His-Avi
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Biotinylated Human IL-18BP, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 0.90 nM as determined in SPR assay (Biacore T200).
	Biotinylated Human IL-18BP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Have more questions?

Contact Us

Get in touch

About

Support

Products