Name: Biotinylated Human IL-22R alpha 1&IL-10R beta Protein (ILR-HM5ABB)
Brand: KactusBio
SKU: ILR-HM5ABB-100UG
Price: 600.0 USD
Availability: InStock

Biotinylated Human IL-22R alpha 1&IL-10R beta Protein (ILR-HM5ABB)

Immobilized Human IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-22R alpha1&IL-10R beta, hFc Tag with the EC50 of 1.36ug/ml determined by ELISA.

Biotinylated Human IL-22R alpha 1&IL-10R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human IL-22R alpha 1&IL-10R beta is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-22R alpha1&IL-10R beta, hFc Tag with the EC50 of 1.36ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: His16-Thr228(IL-22R alpha 1) & Met20-Ser220(IL-10R beta)

Catalog #ILR-HM5ABB

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human IL-22R alpha 1&IL-10R beta Protein is expressed from HEK293 with hFc tag and Avi Tag at the C-Terminus.It contains His16-Thr228 (IL-22R alpha 1) and Met20-Ser220 (IL-10R beta).
Product Background	IL-22Rα1&IL-10Rβ are receptors for IL-22 and IL-10, mediate the activation of JAK-STAT, MAPK and other signaling pathways, and participate in the process of many inflammatory diseases. IL-22 Rα1 contains cytoplasmic motifs for interactions with signal transduction molecules, but formation of ternary complexes with IL10 Rβ or IL20 Rβ and the respective ligands is required for signal transduction[1].
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-22R alpha 1&IL-10R beta
Synonyms	IL-22R alpha 1; IL-10R beta; IL-22Rα1&IL-10Rβ
Accession	Q8N6P7(IL-22R alpha 1)&Q08334(IL-10R beta)
Species	Human
Biotinylated	yes
Amino Acid Range	His16-Thr228(IL-22R alpha 1) & Met20-Ser220(IL-10R beta)
Molecular Weight	The protein has a predicted MW of 52.07 kDa (IL-22R alpha 1) and 48.85 kDa (IL-10R beta). Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-22R alpha1&IL-10R beta, hFc Tag with the EC50 of 1.36ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-22R alpha1&IL-10R beta, hFc Tag with the EC50 of 1.36ug/ml determined by ELISA.
	Biotinylated Human IL-22R alpha 1&IL-10R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human IL-22R alpha 1&IL-10R beta is greater than 95% as determined by SEC-HPLC.