Name: Biotinylated Human IL-23R Protein (Primary Amine Labeling) (ILR-HM223B)
Brand: KactusBio
SKU: ILR-HM223B-100UG
Price: 578.0 USD
Availability: InStock

Biotinylated Human IL-23R Protein (Primary Amine Labeling) (ILR-HM223B)

Biotinylated Human IL-23R, hFc Avi Tag captured on CM5 Chip via Protein A can bind Human IL-23 alpha&IL-12 beta, His Tag with an affinity constant of 42.04 nM as determined in SPR assay (Biacore T200).

Biotinylated Human IL-23R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Activity: The affinity constant of 42.04 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gly24-Gly355

Catalog #ILR-HM223B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human IL-23R Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the C-terminus.It contains Gly24-Gly355.
Product Background	Interleukin-23 (IL-23), a member of the IL-12 family of cytokines, is a heterodimeric cytokine. It is composed of subunits p40 (shared with IL-12) and p19 (an IL-12 p35-related subunit) and is secreted by several types of immune cells, such as natural killer cells and dendritic cells. The IL-23 receptor is composed of the subunit IL-12Rβ1 and the IL-23-specific subunit IL-23R. The binding of IL-23 to its specific cell surface receptor regulates a number of functions, including proliferation and differentiation of cells and secretion of cell factors.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-23R
Synonyms	IBD17; IL-23 R; IL-23 receptor
Accession	Q5VWK5-1
Species	Human
Biotinylated	yes
Amino Acid Range	Gly24-Gly355
Molecular Weight	The protein has a predicted MW of 64.81 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 42.04 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Biotinylated Human IL-23R, hFc Avi Tag captured on CM5 Chip via Protein A can bind Human IL-23 alpha&IL-12 beta, His Tag with an affinity constant of 42.04 nM as determined in SPR assay (Biacore T200).
	Biotinylated Human IL-23R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.