Name: Biotinylated Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein (ITG-HM447B)
Brand: KactusBio
SKU: ITG-HM447B-100UG
Price: 660.0 USD
Availability: InStock

Biotinylated Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein (ITG-HM447B)

Immobilized Biotinylated Human ITGA4&ITGB7, His-Avi Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-ITGA4 Antibody, hFc Tag with the EC50 of 2.6ng/ml determined by ELISA.

Biotinylated Human ITGA4&ITGB7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Biotinylated Human ITGA4&ITGB7, His-Avi Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-ITGA4 Antibody, hFc Tag with the EC50 of 2.6ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Tyr34-Thr977(ITGA4) acidic tail & Glu20-His723(ITGB7) basic tail

Catalog #ITG-HM447B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus of ITGA4.It contains Tyr34-Thr977(ITGA4) acidic tail and Glu20-His723(ITGB7) basic tail.
Product Background	Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer
Synonyms	Integrin alpha 4 beta 7; beta7; alpha 4; LPAM; ITGA4&ITGB7;Integrin alpha 4 β 7; β7
Accession	P13612-1(ITGA4)&P26010-1(ITGB7)
Species	Human
Biotinylated	yes
Amino Acid Range	Tyr34-Thr977(ITGA4) acidic tail & Glu20-His723(ITGB7) basic tail
Molecular Weight	The protein has a predicted MW of 112.5 kDa (ITGA4) and 81.3 kDa (ITGB7). Due to glycosylation, the protein migrates to 68-72 kDa, 78-83 kDa, 110-120 kDa and 130-150 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human ITGA4&ITGB7, His-Avi Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-ITGA4 Antibody, hFc Tag with the EC50 of 2.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human ITGA4&ITGB7, His-Avi Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-ITGA4 Antibody, hFc Tag with the EC50 of 2.6ng/ml determined by ELISA.
	Biotinylated Human ITGA4&ITGB7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.