Biotinylated Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein (ITG-HM461B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Phe24-Gly1012 (ITGA6) acidic tail & GIn21-Asp728 (ITGB1) basic tail
Catalog #ITG-HM461B
Regular price $600.00
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Product Description
Recombinant Biotinylated Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe24-Gly1012 (ITGA6) acidic tail and GIn21-Asp728 (ITGB1) basic tail.
Product Background
Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling
Product Category
Recombinant Protein
Target
Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer
Synonyms
α6β1; Integrin alpha 6 beta 1; ITGA6&ITGB1;Integrin alpha 6 β 1
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Phe24-Gly1012 (ITGA6) acidic tail & GIn21-Asp728 (ITGB1) basic tail
Molecular Weight
The protein has a predicted MW of 117.9 kDa (ITGA6) and 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-160 kDa (ITGA6) and 110-150 kDa (ITGB1) under Non reducing (N) condition based on Bis-Tris PAGE result.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human ITGA6&ITGB1 on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%.

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