• Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: His22-His245
Catalog #KIR-HM4L2B
Price
Regular price $577.50
Regular price Sale price $577.50
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Human KIR2DL2 Protein (KIR-HM4L2B) Summary

Product Description

 Recombinant Biotinylated Human KIR2DL2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.

Product Background

 KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery | Others

Biotinylated Human KIR2DL2 Protein (KIR-HM4L2B) Specifications/Details

Protein
 KIR2DL2
Synonyms
 NKAT-6;p58 NK receptor CL-43;CD158b1;KIR2DL2;CD158B1;NKAT6;p58NK receptor CL43
Accession
Species
 Human
Biotinylated
 yes
Amino Acid Range
 His22-His245
Molecular Weight
 The protein has a predicted MW of 27.4 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi

Fluorophore

 Biotin-labeled
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Biotinylated Human KIR2DL2 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. Biotinylated Human KIR2DL2 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Biotinylated-Human KIR2DL2 is greater than 90% as determined by SEC-HPLC. The purity of Biotinylated-Human KIR2DL2 is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...