Biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3B)
Biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly24-Glu439
Catalog #LIL-HM4A3B
Regular price $577.50
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Biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3B) Summary

Product Description

Recombinant Biotinylated Human LILRA3/CD85e Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gly24-Glu439.

Product Background

Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31,- is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains. Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3B) Specifications/Details

Protein
LILRA3/CD85e
Synonyms
CD85e; HM31; HM43; ILT6; ILT-6; LILRA3; LIR4; LIR-4HM43e3
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Gly24-Glu439
Molecular Weight
The protein has a predicted MW of 47.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-His-Avi
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human LILRA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human LILRA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human LILRA3 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human LILRA3 is greater than 95% as determined by SEC-HPLC.
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