Biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3B)
Biotinylated Human LILRA3/CD85e Protein (LIL-HM4A3B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly24-Glu439
Catalog #LIL-HM4A3B
Regular price $525.00
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Product Description

Recombinant Biotinylated Human LILRA3/CD85e Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gly24-Glu439.

Product Background

Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31,- is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains. Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein

LILRA3/CD85e

Synonyms

CD85e; HM31; HM43; ILT6; ILT-6; LILRA3; LIR4; LIR-4HM43e3

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Gly24-Glu439

Molecular Weight

The protein has a predicted MW of 47.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human LILRA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human LILRA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human LILRA3 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human LILRA3 is greater than 95% as determined by SEC-HPLC.

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