• Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Gln22-Lys123
Catalog #LB4-HM4D4B
Price
Regular price $74250
Regular price Sale price $74250
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Human LILRB4/CD85k/ILT3 Domain 1+hinge Protein (LB4-HM4D4B) Summary

Product Description

 Recombinant Biotinylated Human LILRB4/CD85k/ILT3 Domain 1+hinge Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Lys123.

Product Background

 LILRB4,also known as CD85k and LIR-5, ILT3,- is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

Biotinylated Human LILRB4/CD85k/ILT3 Domain 1+hinge Protein (LB4-HM4D4B) Specifications/Details

Protein
 LILRB4/CD85k/ILT3
Synonyms
 HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Accession
Species
 Human
Biotinylated
 yes
Amino Acid Range
 Gln22-Lys123
Molecular Weight
 The protein has a predicted MW of 14.77 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi
Fluorophore
 Biotin-labeled
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Biotinylated Human LILRB4 Domain 1+hinge on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human LILRB4 Domain 1+hinge on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human LILRB4 Domain 1+hinge is greater than 90% as determined by SEC-HPLC. The purity of Biotinylated Human LILRB4 Domain 1+hinge is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...