Product Description |
Recombinant Biotinylated Human LILRB4/CD85k/ILT3 Domain 1+hinge Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Lys123. |
Product Background |
LILRB4,also known as CD85k and LIR-5, ILT3,- is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. |
Product Category |
Recombinant Protein |
Target |
LILRB4/CD85k/ILT3 Domain 1+hinge |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Gln22-Lys123 |
Molecular Weight |
The protein has a predicted MW of 14.77 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Biotinylated Human LILRB4 Domain 1+hinge on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Biotinylated Human LILRB4 Domain 1+hinge is greater than 90% as determined by SEC-HPLC. |
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