Biotinylated Human LILRB4/CD85k/ILT3 Domain 1 Protein (LB4-HM1D1B)
Biotinylated Human LILRB4/CD85k/ILT3 Domain 1 Protein (LB4-HM1D1B)
Biotinylated Human LILRB4/CD85k/ILT3 Domain 1 Protein (LB4-HM1D1B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln22-Thr118
Catalog #LB4-HM1D1B
Regular price $675.00
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Product Description
Recombinant Biotinylated Human LILRB4/CD85k/ILT3 Domain 1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Thr118.
Product Background
LILRB4,also known as CD85k and LIR-5, ILT-3,- is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
Product Category
Recombinant Protein
Target
LILRB4/CD85k/ILT3 Domain 1
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Gln22-Thr118
Molecular Weight
The protein has a predicted MW of 14.26 kDa. Due to glycosylation, the protein migrates to 14.5-20 kDa based on Bis-Tris PAGE result.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Biotinylated Human LILRB4 Domain 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human LILRB4 Domain 1 is greater than 95% as determined by SEC-HPLC.
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