Biotinylated Human MDL-1/CLEC5A Protein (CLE-HM45AB)
  • Express System: HEK293
  • Product Tag: N-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Pro28-Lys188
Catalog #CLE-HM45AB
Regular price $578.00
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Product Description

Recombinant Biotinylated Human MDL-1/CLEC5A Protein is expressed from HEK293 with His tag and Avi tag at the N-terminus.It contains Pro28-Lys188.

Product Background

In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.

Product Category

Recombinant Protein / Antibody discovery

Protein

MDL-1/CLEC5A

Synonyms

MDL-1; CLECSF5; MDL1; CLEC5A; DAP12-associating lectin 1

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Pro28-Lys188

Molecular Weight

The protein has a predicted MW of 21.3 kDa. Due to glycosylation, the protein migrates to 43-53 kDa based on Bis-Tris PAGE result.

Product Tag

N-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human MDL-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human MDL-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human MDL-1 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human MDL-1 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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