Name: Biotinylated Human/Mouse/Rat GDF-8 Protein (GDF-HM008B)
Brand: KactusBio
SKU: GDF-HM008B-100UG
Price: 990.0 USD
Availability: InStock

Biotinylated Human/Mouse/Rat GDF-8 Protein (GDF-HM008B)

Immobilized Human/Cynomolgus Activin RIIB, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 2.5ng/ml determined by ELISA.

Immobilized Human/Cynomolgus Activin RIIA, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 9.1ng/ml determined by ELISA (QC Test).

Immobilized Biotinylated Human/Mouse/Rat GDF-8, Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 12.8ng/ml determined by ELISA.

Biotinylated Human/Mouse/Rat GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Loaded Human/Cynomolgus Activin RIIB, hFc Tag on ProA-Biosensor can bind Biotinylated Human/Mouse/Rat GDF-8, His Tag with an affinity constant of 0.22 nM as determined in BLI assay (Gator® Prime).

Loaded Anti-GDF8 Ab., hFc Tag on ProA-Biosensor can bind Biotinylated Human/Mouse/Rat GDF-8, His Tag with an affinity constant of 0.49 nM as determined in BLI assay (Gator® Prime).

Express System: HEK293
Product Tag: C-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human/Cynomolgus Activin RIIB, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 2.5ng/ml determined by ELISA.
Amino Acid Range: Asp267-Ser375 (Human) / Asp268-Ser376 (Mouse/Rat)
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Catalog #GDF-HM008B

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Biotinylated Human/Mouse/Rat GDF-8 Protein (GDF-HM008B) Summary

Product Description	Recombinant Biotinylated Human/Mouse/Rat GDF-8 Protein is expressed from HEK293 with Avi tag at the C-terminus.It contains Asp267-Ser375 (Human) / Asp268-Ser376 (Mouse/Rat).
Product Background	Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Biotinylated Human/Mouse/Rat GDF-8 Protein (GDF-HM008B) Specifications/Details

Protein	GDF-8
Synonyms	Myostatin; GDF8; Mstn; GDF-8; Myostatin
Accession	O14793(Human) / O08689(Mouse) / O35312(Rat)
Species	Human/Mouse/Rat
Biotinylated	yes
Amino Acid Range	Asp267-Ser375 (Human) / Asp268-Ser376 (Mouse/Rat)
Molecular Weight	The protein has a predicted MW of 14.21 kDa. Due to glycosylation, the protein migrates to 15-18 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human/Cynomolgus Activin RIIB, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 2.5ng/ml determined by ELISA.
Product Tag	C-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 4mM HCL.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human/Cynomolgus Activin RIIB, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 2.5ng/ml determined by ELISA.
	Immobilized Human/Cynomolgus Activin RIIA, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 9.1ng/ml determined by ELISA (QC Test).
	Immobilized Biotinylated Human/Mouse/Rat GDF-8, Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 12.8ng/ml determined by ELISA.
	Biotinylated Human/Mouse/Rat GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human/Cynomolgus Activin RIIB, hFc Tag on ProA-Biosensor can bind Biotinylated Human/Mouse/Rat GDF-8, His Tag with an affinity constant of 0.22 nM as determined in BLI assay (Gator® Prime).
	Loaded Anti-GDF8 Ab., hFc Tag on ProA-Biosensor can bind Biotinylated Human/Mouse/Rat GDF-8, His Tag with an affinity constant of 0.49 nM as determined in BLI assay (Gator® Prime).