Biotinylated Human/Mouse/Rat GDF-8 Protein (GDF-HM008B)
  • Express System: HEK293
  • Product Tag: C-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human/Cynomolgus Activin RIIA, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 9.1ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Asp267-Ser375 (Human) / Asp268-Ser376 (Mouse/Rat)
Catalog #GDF-HM008B
Regular price $990.00
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Biotinylated Human/Mouse/Rat GDF-8 Protein (GDF-HM008B) Summary

Product Description

Recombinant Biotinylated Human/Mouse/Rat GDF-8 Protein is expressed from HEK293 with Avi tag at the C-terminus.It contains Asp267-Ser375 (Human) / Asp268-Ser376 (Mouse/Rat).

Product Background

Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Biotinylated Human/Mouse/Rat GDF-8 Protein (GDF-HM008B) Specifications/Details

Protein
GDF-8
Synonyms
Myostatin; GDF8; Mstn; GDF-8; Myostatin
Accession
Species
Human/Mouse/Rat
Biotinylated
yes
Amino Acid Range
Asp267-Ser375 (Human) / Asp268-Ser376 (Mouse/Rat)
Molecular Weight
The protein has a predicted MW of 14.21 kDa. Due to glycosylation, the protein migrates to 15-18 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human/Cynomolgus Activin RIIA, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 9.1ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-Avi
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 4mM HCL.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human/Cynomolgus Activin RIIA, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 9.1ng/ml determined by ELISA (QC Test). Immobilized Human/Cynomolgus Activin RIIA, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat GDF-8, Avi Tag with the EC50 of 9.1ng/ml determined by ELISA (QC Test).
Immobilized Biotinylated Human/Mouse/Rat GDF-8, Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 3.2ng/ml determined by ELISA. Immobilized Biotinylated Human/Mouse/Rat GDF-8, Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 3.2ng/ml determined by ELISA.
Immobilized Biotinylated Human/Mouse/Rat GDF-8, Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 12.8ng/ml determined by ELISA. Immobilized Biotinylated Human/Mouse/Rat GDF-8, Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 12.8ng/ml determined by ELISA.
Biotinylated Human/Mouse/Rat GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human/Mouse/Rat GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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