• Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Biotinylated Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 3.2ng/ml determined by ELISA (QC Test).
  • Negative Control: Biotinylated Nanodisc Control (CON-HM1NB)
  • Amino Acid Range: Met1-Val330
Catalog #MR2-HM10XN
Price
Regular price $2,16590
Regular price Sale price $2,16590
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Human MRGPRX2 Nanodisc (MR2-HM10XN) Summary

Product Description

 Recombinant Biotinylated Human MRGPRX2 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val330.

Product Background

 As receptor for multiple drugs, MRGPRX2 is crucial to drug-induced hypersensitivity. However, not only drugs, but also endogenous mediators like neuropeptides and host defense peptides activate MRGPRX2, suggesting its broad impact in cutaneous pathophysiology.

Biotinylated Human MRGPRX2 Nanodisc (MR2-HM10XN) Specifications/Details

Protein
 MRGPRX2
Synonyms
 MRGX2
Accession
Species
 Human
Biotinylated
 yes
Amino Acid Range
 Met1-Val330
Molecular Weight
 The protein has a predicted MW of 50.1 kDa.
Activity
 Immobilized Biotinylated Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 3.2ng/ml determined by ELISA (QC Test).
Product Tag
 C-His
Fluorophore
 Biotin-labeled
Expression System
 HEK293
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
 Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Biotinylated Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 3.2ng/ml determined by ELISA (QC Test). Immobilized Biotinylated Human MRGPRX2 Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-MRGPRX2 Antibody, mFc Tag with the EC50 of 3.2ng/ml determined by ELISA (QC Test).
Loaded Biotinylated Human MRGPRX2 Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-MRGPRX2 Antibody, mFc Tag with an affinity constant of 0.25 nM as determined in BLI assay . Loaded Biotinylated Human MRGPRX2 Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-MRGPRX2 Antibody, mFc Tag with an affinity constant of 0.25 nM as determined in BLI assay .
Other Available Proteins:
Finding available proteins...