Biotinylated Human NRG1 Beta 1 Protein (Primary Amine Labeling) (NRG-HM201B)

  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Biotinylated: yes
  • Activity: Immobilized Human Her4, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 0.2ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Ser2-Lys246

Catalog: NRG-HM201B

$525.00
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Product Description Recombinant Biotinylated Human NRG1 Beta 1 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the N-terminus.It contains Ser2-Lys246.

Product Background

Neuregulin-1 (NRG-1) is a ligand of the epidermal growth factor receptor (erbB), and its interaction involves activation of the glutamatergic N-methyl-Daspartate receptor, which increases the expression of the β2 subunit of the γ- aminobutyric acid receptor and subunits of the nicotinic acetylcholine receptor.

Product Category

Recombinant Protein

Target

NRG1 Beta 1

Gene/Protein ID

Q02297-6

Species

Human

Exact Sequence

Ser2-Lys246
Molecular Weight The protein has a predicted MW of 54.00 kDa. Due to glycosylation, the protein migrates to 75-90 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human Her4, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 0.2ug/ml determined by ELISA. See testing image for detail.

Product Tag

N-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Her4, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 0.2ug/ml determined by ELISA.
The purity of Biotinylated Human NRG1 Beta 1 is greater than 95% as determined by SEC-HPLC.
Biotinylated Human NRG1 Beta 1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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