Name: Biotinylated Human Oncostatin M/OSM Protein (ONM-HM401B)
Brand: KactusBio
SKU: ONM-HM401B-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human Oncostatin M/OSM Protein (ONM-HM401B)

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 0.94 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ala26-Arg221

Catalog #ONM-HM401B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human Oncostatin M/OSM Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Arg221.
Product Background	OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Product Category	Recombinant Protein

Target	Oncostatin M/OSM
Synonyms	Oncostatin M; OSM; MGC20461
Accession	P13725
Species	Human
Biotinylated	yes
Amino Acid Range	Ala26-Arg221
Molecular Weight	The protein has a predicted MW of 25.1 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.94 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His-Avi
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human LIF R, His Tag immobilized on CM5 Chip can bind Biotinylated Human Oncostatin M, His Tag with an affinity constant of 0.94 uM as determined in SPR assay (Biacore T200).
	Biotinylated Oncostatin M on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of Biotinylated Oncostatin M is greater than 95% as determined by SEC-HPLC.

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