Biotinylated Human OSMR beta Protein (OSM-HM001B)
  • Express System: HEK293
  • Product Tag: C-Avi
  • Purity: >95% as determined by Bis-Tris PAGE;>90% as determined by HPLC
  • Activity: Immobilized Biotinylated Human OSMR beta, Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Glu28-Met740
Catalog #OSM-HM001B
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Product Description
 Recombinant Biotinylated Human OSMR beta Protein is expressed from HEK293 with Avi tag at the C-terminus.It contains Glu28-Met740.
Product Background
 OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Product Category
 Recombinant Protein
Target
 OSMR beta
Synonyms
 IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ;IL-31R subunit β; IL-31R-β; OSMR β
Accession
Species
 Human
Biotinylated
 yes
Amino Acid Range
 Glu28-Met740
Molecular Weight
 The protein has a predicted MW of 82.93 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Biotinylated Human OSMR beta, Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
 C-Avi
Express System
 HEK293
Purity
 >95% as determined by Bis-Tris PAGE;>90% as determined by HPLC
Endotoxin
 Less than 0.1EU per ug by the LAL method.
Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Biotinylated Human OSMR beta, Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA (QC Test).
Biotinylated Human OSMR beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human OSMR beta is greater than 90% as determined by SEC-HPLC.

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