Biotinylated Human OSMR Protein (OSM-HM401B)
Catalog: OSM-HM401B
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Product Description | Recombinant Biotinylated Human OSMR Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Glu28-Met740. |
Product Background |
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death. |
Product Category |
Recombinant Protein |
Target |
OSMR |
Accession | |
Species |
Human |
Amino Acid Range |
Glu28-Met740 |
Molecular Weight | The protein has a predicted MW of 84.03 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Biotinylated Human OSMR, His Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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