Name: Biotinylated Human PLAU/uPA Protein (active form) (PLA-HM401B)
Brand: KactusBio
SKU: PLA-HM401B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human PLAU/uPA Protein (active form) (PLA-HM401B)

Biotinylated Human PLAU on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Measured by its ability to cleave a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The specific activity is >2000 pmol/min/ug.
Amino Acid Range: Ser21-Leu431

Catalog #PLA-HM401B

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Biotinylated Human PLAU/uPA Protein (active form) (PLA-HM401B) Summary

Product Description	Recombinant Biotinylated Human PLAU/uPA Protein (active form) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser21-Leu431, which consists of two chains: Long chain A (Ser21-Phe177) and chain B (Ile179-Leu 431). The long chain A is further cleaved to yield a short chain A (Lys156-Phe 177) and N-Terminus fragment (Ser21-Lys155).
Product Background	Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Biotinylated Human PLAU/uPA Protein (active form) (PLA-HM401B) Specifications/Details

Protein	PLAU/uPA
Synonyms	PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD
Accession	P00749-1
Species	Human
Biotinylated	yes
Amino Acid Range	Ser21-Leu431
Molecular Weight	The protein has a predicted MW of 49.3 kDa. Due to protein lysis and glycosylation, the protein migrates to 23-27 kDa, 35-40 kDa based on Bis-Tris PAGE result.
Activity	Measured by its ability to cleave a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The specific activity is >2000 pmol/min/ug.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM NaAc, 150mM NaCl (pH 5.0).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.