Name: Biotinylated Human PRLR Protein (PLR-HM401B)
Brand: KactusBio
SKU: PLR-HM401B-100UG
Price: 578.0 USD
Availability: InStock

Biotinylated Human PRLR Protein (PLR-HM401B)

Immobilized Biotinylated Human PRLR, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA.

Biotinylated Human PRLR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human PRLR is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Biotinylated Human PRLR, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA.
Amino Acid Range: Gln25-Asp234
Other Available Proteins:

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Catalog #PLR-HM401B

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Biotinylated Human PRLR Protein (PLR-HM401B) Summary

Product Description	Recombinant Biotinylated Human PRLR Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln25-Asp234.
Product Background	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target. Bispecific antibodies (BsAbs) could guide immune cells toward tumor cells, and produced remarkable effects in some cancers.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Biotinylated Human PRLR Protein (PLR-HM401B) Specifications/Details

Protein	PRLR
Synonyms	PRL-R; HPRL; MFAB; Prolactin R
Accession	P16471-1
Species	Human
Biotinylated	yes
Amino Acid Range	Gln25-Asp234
Molecular Weight	The protein has a predicted MW of 27.32 kDa. Due to glycosylation, the protein migrates to 32-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human PRLR, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 50mM Tris, 150mM NaCl (pH 7.5).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Biotinylated Human PRLR, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA.
	Biotinylated Human PRLR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human PRLR is greater than 95% as determined by SEC-HPLC.