Name: Biotinylated Human Siglec-10 Protein (SIG-HM510B)
Brand: KactusBio
SKU: SIG-HM510B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human Siglec-10 Protein (SIG-HM510B)

Immobilized Anti-Siglec-10 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Siglec-10, hFc Tag with the EC50 of 0.33ug/ml determined by ELISA.

Biotinylated Human Siglec-10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-hFc-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Anti-Siglec-10 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Siglec-10, hFc Tag with the EC50 of 0.33ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Met17-Thr546

Catalog #SIG-HM510B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human Siglec-10 Protein is expressed from HEK293 with hFc tag and Avi tag at the C-Terminus.It contains Met17-Thr546.
Product Background	Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
Product Category	Recombinant Protein / Antibody discovery

Protein	Siglec-10
Synonyms	SLG2; SIGLEC10; MGC126774; PRO940
Accession	Q96LC7-1
Species	Human
Biotinylated	yes
Amino Acid Range	Met17-Thr546
Molecular Weight	The protein has a predicted MW of 85.8 kDa. Due to glycosylation, the protein migrates to 95-110 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Anti-Siglec-10 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Siglec-10, hFc Tag with the EC50 of 0.33ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS, 500mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Anti-Siglec-10 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Siglec-10, hFc Tag with the EC50 of 0.33ug/ml determined by ELISA.
	Biotinylated Human Siglec-10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.