Biotinylated Human SIRP Beta 1 Isoform 3 Protein (SRP-HM4BLB)
Catalog: SRP-HM4BLB
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| Product Description | Recombinant Biotinylated Human SIRP Beta 1 Isoform 3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Leu371. |
Product Background |
Signal regulatory protein β1 (SIRPB1) is a signal regulatory protein member of the immunoglobulin superfamily and is capable of modulating receptor tyrosine kinase-coupled signaling. Copy number variations at the SIRPB1 locus were previously reported to associate with prostate cancer aggressiveness in patients.SIRPB1 gene amplification and overexpression were detected in prostate cancer specimens. The knockdown of SIRPB1 significantly suppressed cell growth in colony formation assays and cell mobility. |
Product Category |
Recombinant Protein |
Target |
SIRP Beta 1 Isoform 3 |
| Synonyms | SIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a |
Gene/Protein ID |
Q5TFQ8-1 |
Species |
Human |
Exact Sequence |
Glu30-Leu371 |
| Molecular Weight | The protein has a predicted MW of 39.9 kDa. Due to glycosylation, the protein migrates to 55-68 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Biotinylated Human SIRP Beta 1 Isoform 3 is greater than 95% as determined by SEC-HPLC. |
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Biotinylated Human SIRP Beta 1 Isoform 3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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