Biotinylated Human SIRP Beta 1 Isoform 3 Protein (SRP-HM4BLB)
Biotinylated Human SIRP Beta 1 Isoform 3 Protein (SRP-HM4BLB)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu30-Leu371
Catalog #SRP-HM4BLB
Regular price $525.00
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Product Description
Recombinant Biotinylated Human SIRP Beta 1 Isoform 3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Leu371.
Product Background
Signal regulatory protein β1 (SIRPB1) is a signal regulatory protein member of the immunoglobulin superfamily and is capable of modulating receptor tyrosine kinase-coupled signaling. Copy number variations at the SIRPB1 locus were previously reported to associate with prostate cancer aggressiveness in patients.SIRPB1 gene amplification and overexpression were detected in prostate cancer specimens. The knockdown of SIRPB1 significantly suppressed cell growth in colony formation assays and cell mobility.
Product Category
Recombinant Protein
Target
SIRP Beta 1 Isoform 3
Synonyms
SIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Glu30-Leu371
Molecular Weight
The protein has a predicted MW of 39.9 kDa. Due to glycosylation, the protein migrates to 55-68 kDa based on Bis-Tris PAGE result.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Biotinylated Human SIRP Beta 1 Isoform 3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human SIRP Beta 1 Isoform 3 is greater than 95% as determined by SEC-HPLC.

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