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Biotinylated Human NaPi2b/SLC34A2 Nanodisc (SLC-HM1ANB) Summary
Product Description |
Recombinant Biotinylated Human NaPi2b/SLC34A2 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Leu689. |
Product Background |
SLC34A2, a member of the SLC34 family, is a multipass membrane protein and encodes a type 2b sodium-dependent phosphate transporter, NaPiIIb. It is known that SLC34A2 can mediate transporting inorganic phosphate into epithelial cells via sodium ion cotransport. SLC34A2 also strongly inhibited tumor growth and metastasis ability in an A549 subcutaneous tumor model and lung metastasis mode. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc |
Biotinylated Human NaPi2b/SLC34A2 Nanodisc (SLC-HM1ANB) Specifications/Details
Protein |
NaPi2b/SLC34A2 |
Synonyms |
NaPi-2b; NaPi 2b; NAPI-IIb; NPTIIb; NaPi2b; PULAM; |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Met1-Leu689 |
Molecular Weight |
The protein has a predicted MW of 88.6 kDa. |
Activity |
Immobilized Biotinylated Human NaPi2b Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Lifastuzumab, hFc Tag with the EC50 of 10.8ng/ml determined by ELISA. The affinity constant of 2.64 nM as determined in SPR assay (Biacore T200). |
Product Tag |
C-His |
Fluorophore |
Biotin-labeled |
Expression System |
HEK293 |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Biotinylated Human NaPi2b Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Lifastuzumab, hFc Tag with an affinity constant of 2.64 nM as determined in SPR assay (Biacore T200). |
|
|
Immobilized Biotinylated Human NaPi2b Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Lifastuzumab, hFc Tag with the EC50 of 10.8ng/ml determined by ELISA. |
|
|
Immobilized Biotinylated Human NaPi2b Nanodisc, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-SLC34A2 Antibody 2, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA. |
Other Available Proteins:
Finding available proteins...
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