- Express System: HEK293
- Purity: > 95% as determined by HPLC
- Activity: Immobilized Biotinylated Human STEAP1 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Vandortuzumab, hFc Tag with the EC50 of 91.2ng/ml determined by ELISA. See testing image for detail.
- Amino Acid Range: Met1-Leu339
Biotinylated Human STEAP1 VLP (STP-HM00VB) Summary
Product Description |
Recombinant Biotinylated Human STEAP1 VLP is expressed from HEK293.It contains Met1-Leu339 (It may have cross reaction with anti-His antibody). |
Product Background |
Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP |
Biotinylated Human STEAP1 VLP (STP-HM00VB) Specifications/Details
Protein |
STEAP1 |
Synonyms |
PRSS24; STEAP; PRSS24, STEAP 1 |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Met1-Leu339 |
Molecular Weight |
The protein has a predicted MW of 43.06 kDa. |
Activity |
Immobilized Biotinylated Human STEAP1 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Vandortuzumab, hFc Tag with the EC50 of 91.2ng/ml determined by ELISA. See testing image for detail. |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 300mM L-Arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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