Name: Biotinylated Human TREM2 Protein (TRM-HM401B)
Brand: KactusBio
SKU: TRM-HM401B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human TREM2 Protein (TRM-HM401B)

Immobilized Biotinylated Human TREM2, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-TREM2 Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA.

Biotinylated Human TREM2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Biotinylated Human TREM2, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-TREM2 Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: His19-Ser174

Catalog #TRM-HM401B

Size

100UG

500UG

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Biotinylated Human TREM2 Protein (TRM-HM401B) Summary

Product Description	Recombinant Biotinylated Human TREM2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His19-Ser174.
Product Background	TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2- consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Biotinylated Human TREM2 Protein (TRM-HM401B) Specifications/Details

Protein	TREM2
Synonyms	PLOSL2; TREM2; TREM-2; Trem2a; Trem2b; Trem2c
Accession	Q9NZC2-1
Species	Human
Biotinylated	yes
Amino Acid Range	His19-Ser174
Molecular Weight	The protein has a predicted MW of 20.3 kDa. Due to glycosylation, the protein migrates to 30-45 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human TREM2, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-TREM2 Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human TREM2, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-TREM2 Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA.
	Biotinylated Human TREM2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.