Biotinylated Mouse FGFR3 alpha (IIIb) Protein (Primary Amine Labeling) (FGF-MM43BB)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Pro22-Val349
Catalog #FGF-MM43BB
Regular price $900.00
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Product Description
Recombinant Biotinylated Mouse FGFR3 alpha (IIIb) Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-terminus.It contains Pro22-Val349.
Product Background
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts.
Product Category
Recombinant Protein
Target
FGFR3 alpha (IIIb)
Accession
Species
Mouse
Biotinylated
yes
Amino Acid Range
Pro22-Val349
Molecular Weight
The protein has a predicted MW of 37.09 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Biotinylated Mouse FGFR3 alpha (IIIb) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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