Biotinylated Mouse IL-17A/CTLA-8 Protein (ILA-MM417B)
Biotinylated Mouse IL-17A/CTLA-8 Protein (ILA-MM417B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Mouse IL-17R alpha at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse IL-17A, His Tag with the EC50 of 28.3ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Ala26-Ala158
Catalog #ILA-MM417B
Regular price $525.00
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Product Description

Recombinant Biotinylated Mouse IL-17A/CTLA-8 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Ala158.

Product Background

Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

Product Category

Recombinant Protein / Antibody discovery

Protein

IL-17A/CTLA-8

Synonyms

CTLA-8; IL17; IL17A; IL-17CTLA-8; interleukin 17A

Accession

Species

Mouse

Biotinylated

yes

Amino Acid Range

Ala26-Ala158

Molecular Weight

The protein has a predicted MW of 18 kDa. Due to glycosylation, the protein migrates to 19-29 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Mouse IL-17R alpha at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse IL-17A, His Tag with the EC50 of 28.3ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Mouse IL-17R alpha at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse IL-17A, His Tag with the EC50 of 28.3ng/ml determined by ELISA. Immobilized Mouse IL-17R alpha at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse IL-17A, His Tag with the EC50 of 28.3ng/ml determined by ELISA.
Biotinylated Mouse IL-17A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Mouse IL-17A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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support@kactusbio.us

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