Biotinylated Mouse IL-5 Protein (IL5-MM401B)
  • Express System: HEK293
  • Product Tag: N-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: The affinity constant of 0.511 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Met21-Gly133
Catalog #IL5-MM401B
Regular price $525.00
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Product Description

Recombinant Biotinylated Mouse IL-5 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Met21-Gly133.

Product Background

IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).

Product Category

Recombinant Protein / Antibody discovery

Protein

IL-5

Synonyms

Interleukin-5; IL-5; T-cell replacing factor; TRF; EDF

Accession

Species

Mouse

Biotinylated

yes

Amino Acid Range

Met21-Gly133

Molecular Weight

The protein has a predicted MW of 16.03 kDa. Due to glycosylation, the protein migrates to 16 kDa and 20-35 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 0.511 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

N-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl, 10% Glycerol (pH 7.0).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IL-5 R alpha, His Tag immobilized on CM5 Chip can bind Biotinylated Mouse IL-5, His-Avi Tag with an affinity constant of 0.511 uM as determined in SPR assay (Biacore T200). Mouse IL-5 R alpha, His Tag immobilized on CM5 Chip can bind Biotinylated Mouse IL-5, His-Avi Tag with an affinity constant of 0.511 uM as determined in SPR assay (Biacore T200).
Biotinylated Mouse IL-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Mouse IL-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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