Biotinylated Mouse MDL-1/CLEC5A Protein (CLE-MM45AB)
  • Express System: HEK293
  • Product Tag: N-His-Avi
  • Purity: >95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Tyr26-Lys190
Catalog #CLE-MM45AB
Regular price $525.00
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Product Description
Recombinant Biotinylated Mouse MDL-1/CLEC5A Protein is expressed from HEK293 with His tag and Avi tag at the N-terminus.It contains Tyr26-Lys190.
Product Background
In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.
Product Category
Recombinant Protein
Target
MDL-1/CLEC5A
Synonyms
MDL-1; CLECSF5; MDL1; CLEC5A; DAP12-associating lectin 1
Accession
Species
Mouse
Biotinylated
yes
Amino Acid Range
Tyr26-Lys190
Molecular Weight
The protein has a predicted MW of 21.76 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.
Product Tag
N-His-Avi
Express System
HEK293
Purity
>95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Biotinylated Mouse MDL-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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