Biotinylated Mouse MDL-1/CLEC5A Protein (CLE-MM45AB)
  • Express System: HEK293
  • Product Tag: N-His-Avi
  • Purity: >95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Tyr26-Lys190
Catalog #CLE-MM45AB
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Product Description
 Recombinant Biotinylated Mouse MDL-1/CLEC5A Protein is expressed from HEK293 with His tag and Avi tag at the N-terminus.It contains Tyr26-Lys190.
Product Background
 In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.
Product Category
 Recombinant Protein
Target
 MDL-1/CLEC5A
Accession
Species
 Mouse
Biotinylated
 yes
Amino Acid Range
 Tyr26-Lys190
Molecular Weight
 The protein has a predicted MW of 21.76 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.
Product Tag
 N-His-Avi
Express System
 HEK293
Purity
 >95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Mouse MDL-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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