Product Description |
Recombinant Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.; It contains His23-Pro296(Qa-1b), Ile21-Met119(B2M) and AMAPRTLLL peptide. |
Product Background |
Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells. |
Product Category |
Recombinant Protein / Antibody discovery / MHC |
Protein |
Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer |
Synonyms |
Qdm; Qa-1b; MHC; H2-T23 |
MHC Form |
Monomer |
Allele |
Qa-1b |
Accession |
P06339(Q1-1b)&P01887(B2M)&AMAPRTLLL |
Species |
Mouse |
Biotinylated |
yes |
Amino Acid Range |
His23-Pro296(Qa-1b), Ile21-Met119(B2M) and AMAPRTLLL peptide |
Molecular Weight |
The protein has a predicted MW of 50.60 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His-Avi |
Expression System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Additional Information
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed