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Biotinylated Mouse SOST/Sclerostin Protein (SOT-MM401B) Summary
Product Description |
Recombinant Biotinylated Mouse SOST/Sclerostin Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln24-Tyr211. |
Product Background |
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Biotinylated Mouse SOST/Sclerostin Protein (SOT-MM401B) Specifications/Details
Protein |
SOST/Sclerostin |
Synonyms |
sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH |
Accession |
|
Species |
Mouse |
Biotinylated |
yes |
Amino Acid Range |
Gln24-Tyr211 |
Molecular Weight |
The protein has a predicted MW of 24.04 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Biotinylated Mouse SOST, His Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human LRP-6, mFc Tag with the EC50 of 13.2ng/ml determined by ELISA. |
Product Tag |
N-His-Avi |
Fluorophore |
Biotin-labeled |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Biotinylated Mouse SOST, His Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human LRP-6, mFc Tag with the EC50 of 13.2ng/ml determined by ELISA. |
|
|
Biotinylated Mouse SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
Other Available Proteins:
Finding available proteins...
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