• Express System: HEK293
  • Product Tag: N-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Biotinylated Mouse SOST, His Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human LRP-6, mFc Tag with the EC50 of 13.2ng/ml determined by ELISA.
  • Amino Acid Range: Gln24-Tyr211
Catalog #SOT-MM401B
Price
Regular price $578.00
Regular price Sale price $578.00
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Mouse SOST/Sclerostin Protein (SOT-MM401B) Summary

Product Description

 Recombinant Biotinylated Mouse SOST/Sclerostin Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln24-Tyr211.

Product Background

 SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery | Others

Biotinylated Mouse SOST/Sclerostin Protein (SOT-MM401B) Specifications/Details

Protein
 SOST/Sclerostin
Synonyms
 sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH
Accession
Species
 Mouse
Biotinylated
 yes
Amino Acid Range
 Gln24-Tyr211
Molecular Weight
 The protein has a predicted MW of 24.04 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Biotinylated Mouse SOST, His Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human LRP-6, mFc Tag with the EC50 of 13.2ng/ml determined by ELISA.
Product Tag
 N-His-Avi

Fluorophore

 Biotin-labeled
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Biotinylated Mouse SOST, His Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human LRP-6, mFc Tag with the EC50 of 13.2ng/ml determined by ELISA. Immobilized Biotinylated Mouse SOST, His Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human LRP-6, mFc Tag with the EC50 of 13.2ng/ml determined by ELISA.
Biotinylated Mouse SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Mouse SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Other Available Proteins:
Finding available proteins...
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