Biotinylated Rat GDF15 Protein (Primary Amine Labeling) (GDF-RE115B)
|Recombinant Biotinylated Rat GDF15 Protein (Primary Amine Labeling) is expressed from E.coli with His tag at the N-terminus.It contains Ser189-Ala303.
|Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
|The protein has a predicted MW of 13.68 kDa. The protein migrates to 14-17 kDa under reduced (R) condition and 25-30 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
|Immobilized Human GFRAL, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Rat GDF15, His Tag with the EC50 of 4.4ng/ml determined by ELISA. See testing image for detail.
|> 95% as determined by Tris-Bis PAGE
|Less than 1EU per ug by the LAL method.
|Shipped with dry ice.
|Supplied as 0.22 um filtered solution in 50mM HAc.
|Stability And Storage
|Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.