Name: Canine BMPR1A/ALK-3 Protein (ALK-DM201)
Brand: KactusBio
SKU: ALK-DM201-100UG
Price: 345.0 USD
Availability: InStock

Catalog #ALK-DM201

Size

100UG

500UG

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Product Description	Recombinant Canine BMPR1A/ALK-3 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln24-Arg152.
Product Background	The type IA bone morphogenetic protein receptor (Bmpr1a), encoded by 11 exons and spanning about 40 kb on chromosome 14 in mice and chromosome 10 in human (Derynck & Feng, 1997; Mishina, Hanks, Miura, Tallquist, & Behringer, 2002), is an essential receptor for BMP signaling.
Product Category	Recombinant Protein / Antibody discovery

Protein	BMPR1A/ALK-3
Synonyms	BMPR1A; ALK-3; ALK3; ALK 3
Accession	NP_001138622.1
Species	Canine
Biotinylated	no
Amino Acid Range	Gln24-Arg152
Molecular Weight	The protein has a predicted MW of 40.94 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Canine BMPR1A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Measured by its ability to inhibit rhBMP4-induced alkaline phosphatase production by ATDC5 cells. The ED50-for this effect is typically 0.5 - 2.5 ug/mL in the presence of 50 ng/mL of recombinant human BMP4.
	The purity of Canine BMPR1A is greater than 95% as determined by SEC-HPLC.