Canine c-MPL/Thrombopoietin R Protein (MPL-DM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln22-Trp489

Catalog: MPL-DM101


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Product Description Recombinant Canine c-MPL/Thrombopoietin R Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln22-Trp489.

Product Background

The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.

Product Category

Recombinant Protein


c-MPL/Thrombopoietin R



Amino Acid Range

Molecular Weight The protein has a predicted MW of 54.45 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.

Product Tag


Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Canine c-MPL is greater than 95% as determined by SEC-HPLC.
Canine c-MPL on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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