Canine c-MPL/Thrombopoietin R Protein (MPL-DM101)
Canine c-MPL/Thrombopoietin R Protein (MPL-DM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln22-Trp489
Catalog #MPL-DM101
Regular price $345.00
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Product Description

Recombinant Canine c-MPL/Thrombopoietin R Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln22-Trp489.

Product Background

The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.

Product Category

Recombinant Protein / Antibody discovery

Protein

c-MPL/Thrombopoietin R

Synonyms

TPO-R; CD110; MPL; c-Mpl; MPLV; K12

Accession

Species

Canine

Biotinylated

no

Amino Acid Range

Gln22-Trp489

Molecular Weight

The protein has a predicted MW of 54.45 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Canine c-MPL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Canine c-MPL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Canine c-MPL is greater than 95% as determined by SEC-HPLC. The purity of Canine c-MPL is greater than 95% as determined by SEC-HPLC.

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