Canine CRTAM Protein (CRM-DM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Phe18-Gly287
Catalog #CRM-DM101
Regular price $346.50
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Canine CRTAM Protein (CRM-DM101) Summary

Product Description

Recombinant Canine CRTAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe18-Gly287.

Product Background

Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Canine CRTAM Protein (CRM-DM101) Specifications/Details

Protein
CRTAM
Synonyms
CD355 antigen; CD355; CRTAM
Accession
Species
Canine
Biotinylated
no
Amino Acid Range
Phe18-Gly287
Molecular Weight
The protein has a predicted MW of 31.19 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Canine CRTAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Canine CRTAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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