Name: Canine CRTAM Protein (CRM-DM101)
Brand: KactusBio
SKU: CRM-DM101-100UG
Price: 346.5 USD
Availability: InStock

Catalog #CRM-DM101

Size

100UG

500UG

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Product Description	Recombinant Canine CRTAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe18-Gly287.
Product Background	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	CRTAM
Synonyms	CD355 antigen; CD355; CRTAM
Accession	E2QWY2
Species	Canine
Biotinylated	no
Amino Acid Range	Phe18-Gly287
Molecular Weight	The protein has a predicted MW of 31.19 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.