Canine EPHA3 Protein (EPH-DM101)
Canine EPHA3 Protein (EPH-DM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Met1-His514
Catalog #EPH-DM101
Regular price $270.00
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Product Description

Recombinant Canine EPHA3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met1-His514.

Product Background

Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (‑295~‑261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.

Product Category

Recombinant Protein / Antibody discovery

Protein

EPHA3

Synonyms

EK4; HEK; ETK; ETK1; EPHA3; TYRO4; HEK4

Accession

Species

Canine

Biotinylated

no

Amino Acid Range

Met1-His514

Molecular Weight

The protein has a predicted MW of 58.97 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Canine EPHA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Canine EPHA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Canine EPHA3 is greater than 95% as determined by SEC-HPLC. The purity of Canine EPHA3 is greater than 95% as determined by SEC-HPLC.

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