Canine IL-13 Protein (IL1-DM113)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
  • Activity: Immobilized Canine IL-13, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-13Ra2, His Tag with the EC50 of 24.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ser19-Arg131
Catalog #IL1-DM113
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Product Description
 Recombinant Canine IL-13 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser19-Arg131.
Product Background
 Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
Product Category
 Recombinant Protein
Target
 IL-13
Synonyms
 IL13; IL-13; interleukin 13; NC30; P600; ALRH; BHR1;
Accession
Species
 Canine
Biotinylated
 no
Amino Acid Range
 Ser19-Arg131
Molecular Weight
 The protein has a predicted MW of 14.05 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Canine IL-13, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-13Ra2, His Tag with the EC50 of 24.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
 C-His
Express System
 HEK293
Purity
 >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Canine IL-13, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-13Ra2, His Tag with the EC50 of 24.6ng/ml determined by ELISA (QC Test).
Canine IL-13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Canine IL-13 is greater than 95% as determined by SEC-HPLC.

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