Canine IL-13 Protein (IL1-DM213)
Canine IL-13 Protein (IL1-DM213)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
  • Activity: Immobilized Canine IL-13, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-13Ra2, His Tag with the EC50 of 5.3ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ser19-Arg131
Catalog #IL1-DM213
Regular price $315.00
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Product Description
Recombinant Canine IL-13 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ser19-Arg131.
Product Background
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
Product Category
Recombinant Protein
Target
IL-13
Synonyms
IL13; IL-13; interleukin 13; NC30; P600; ALRH; BHR1;
Accession
Species
Canine
Biotinylated
no
Amino Acid Range
Ser19-Arg131
Molecular Weight
The protein has a predicted MW of 38.38 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Canine IL-13, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-13Ra2, His Tag with the EC50 of 5.3ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
C-hFc
Express System
HEK293
Purity
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Canine IL-13, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-13Ra2, His Tag with the EC50 of 5.3ng/ml determined by ELISA (QC Test).
Canine IL-13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Canine IL-13 is greater than 95% as determined by SEC-HPLC.

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