Canine IL-31 Protein (IL3-DM101)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ala27-Gln159

Catalog: IL3-DM101


Order now get it on

Product Description Recombinant Canine IL-31 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Ala27-Gln159.

Product Background

Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus. While histamine and neuropeptides have previously been ascribed to play a role in itch that accompanies these diseases, recent evidence suggests that the pruritogenic cytokine interleukin (IL)-31 is a major driver of pruritic responses. IL-31 was originally shown to be produced by activated helper T cells, particularly Th2 cells, mast cells, macrophages and dendritic cells.

Product Category

Recombinant Protein





Amino Acid Range

Molecular Weight The protein has a predicted MW of 16.63 kDa. Due to glycosylation, the protein migrates to 26-36 kDa based on Tris-Bis PAGE result.

Product Tag


Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Canine IL-31 is greater than 95% as determined by SEC-HPLC.
Canine IL-31 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

You may also be interested in