Canine Oncostatin M/OSM-Protein (OSM-DM10M)
Canine Oncostatin M/OSM-Protein (OSM-DM10M)
Canine Oncostatin M/OSM-Protein (OSM-DM10M)
Canine Oncostatin M/OSM-Protein (OSM-DM10M)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser27-Arg207
Catalog #OSM-DM10M
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Product Description
 Recombinant Canine Oncostatin M/OSM-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser27-Arg207.
Product Background
 OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Product Category
 Recombinant Protein
Target
 Oncostatin M/OSM
Accession
Species
 Canine
Biotinylated
 no
Amino Acid Range
 Ser27-Arg207
Molecular Weight
 The protein has a predicted MW of 21.65 kDa. Due to glycosylation, the protein migrates to 27-35 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Canine Oncostatin M on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Canine Oncostatin M is greater than 95% as determined by SEC-HPLC.

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