Name: Canine OSMR-Protein (OSM-DM101)
Brand: KactusBio
SKU: OSM-DM101-100UG
Price: 315.0 USD
Availability: InStock

Catalog #OSM-DM101

Size

100UG

500UG

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Product Description	Recombinant Canine OSMR-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu28-Pro735.
Product Background	OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Product Category	Recombinant Protein / Antibody discovery

Protein	OSMR
Synonyms	IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ;IL-31R subunit β; IL-31R-β; OSMR β
Accession	A0A8I3MI11
Species	Canine
Biotinylated	no
Amino Acid Range	Glu28-Pro735
Molecular Weight	The protein has a predicted MW of 81.73 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Canine OSMR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Canine OSMR is greater than 95% as determined by SEC-HPLC.