Name: Canine PRLR Protein (PLR-DM201)
Brand: KactusBio
SKU: PLR-DM201-100UG
Price: 300.0 USD
Availability: InStock

Catalog #PLR-DM201

Size

100UG

500UG

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Product Description	Recombinant Canine PRLR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln25-Thr235.
Product Background	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target. Bispecific antibodies (BsAbs) could guide immune cells toward tumor cells, and produced remarkable effects in some cancers.
Product Category	Recombinant Protein / Antibody discovery

Protein	PRLR
Synonyms	PRL-R; HPRL; MFAB; Prolactin R
Accession	XM_038663941.1
Species	Canine
Biotinylated	no
Amino Acid Range	Gln25-Thr235
Molecular Weight	The protein has a predicted MW of 53.89 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Canine PRLR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Canine PRLR is greater than 95% as determined by SEC-HPLC.