Name: Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer Protein (MHC-HM104)
Brand: KactusBio
SKU: MHC-HM104-100UG
Price: 310.0 USD
Availability: InStock

Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer Protein (MHC-HM104)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly25-Thr206(Human HLA-A*02:01 α1&α2) & Asp207-Glu299(Mouse H-2Ld α3), Ile21-Met119(mB2M) and KMVELVHFL peptide

Catalog #MHC-HM104

Size

100UG

500UG

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Product Description	Recombinant Chimeric HLA-A02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly25-Thr206 (Human HLA-A02:01 α1&α2) and Asp207-Glu299 (Mouse H-2Ld α3), Ile21-Met119 (mB2M) and KMVELVHFL peptide.
Product Background	Melanoma antigen gene (MAGE)-A2 (MAGEA2) is a member of the MAGE-A family proteins widely studied for cancer vaccine development and identification of tumor markers. MAGEA2 plays an oncogenic role in glioma progression, and they provide insight into MAGEA2 application as a novel predictor of clinical outcomes and a potential glioma biomarker.
Product Category	Recombinant Protein

Target	HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer
MHC Form	Monomer
Allele	HLA-A*02:01
Accession	A0A140T913(Human HLA-A*02:01 α1&α2)&P01897(Mouse H-2Ld α3)&P01887(Mouse B2M)&KMVELVHFL
Species	Human&Mouse
Biotinylated	no
Amino Acid Range	Gly25-Thr206(Human HLA-A*02:01 α1&α2) & Asp207-Glu299(Mouse H-2Ld α3), Ile21-Met119(mB2M) and KMVELVHFL peptide
Molecular Weight	The protein has a predicted MW of 48.00 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer is greater than 95% as determined by SEC-HPLC.

Product Resources

Learn More: MHC Collection Learn More: Peptide-ready MHC Protocol: MHC Staining Case Study: Peptide-ready MHC for TCR Staining Poster: Engineering MHCs as Versatile Reagents

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