Name: Cynomolgus 4-1BB Ligand/TNFSF9 Protein (BBL-CM241)
Brand: KactusBio
SKU: BBL-CM241-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus 4-1BB Ligand/TNFSF9 Protein (BBL-CM241)

Immobilized Cynomolgus/Rhesus macaque 4-1BB, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Cynomolgus 4-1BB Ligand, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA.

Cynomolgus 4-1BB Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus 4-1BB Ligand is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus/Rhesus macaque 4-1BB, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Cynomolgus 4-1BB Ligand, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Arg68-Glu251

Catalog #BBL-CM241

Size

100UG

500UG

Order now, ships by:

[{"id":42618332840158,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"BBL-CM241-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Cynomolgus 4-1BB Ligand\/TNFSF9 Protein (BBL-CM241) - 100UG","public_title":"100UG","options":["100UG"],"price":31500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584248250590,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"BBL-CM241-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Cynomolgus 4-1BB Ligand\/TNFSF9 Protein (BBL-CM241) - 500UG","public_title":"500UG","options":["500UG"],"price":105000,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Cynomolgus 4-1BB Ligand/TNFSF9 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Arg68-Glu251.
Product Background	The 4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. 4-1BB ligand (4-1BBL) is an inducible molecule present on several APC types, including B cells, macrophages and DCs.4-1BB:4-1BBL pathway seems to amplify the existing costimulatory signals, even if the engagement of 4-1BB in the presence of a strong TCR signaling can induce IL-2 production in a CD28-independent manner.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	4-1BB Ligand/TNFSF9
Synonyms	41BB Ligand; 4-1BB Ligand; 4-1BBL; CD137L; TNFSF9
Accession	XP_015296398.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Arg68-Glu251
Molecular Weight	The protein has a predicted MW of 46 kDa. Due to glycosylation, the protein migrates to 50-52 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus/Rhesus macaque 4-1BB, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Cynomolgus 4-1BB Ligand, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus/Rhesus macaque 4-1BB, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Cynomolgus 4-1BB Ligand, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA.
	Cynomolgus 4-1BB Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus 4-1BB Ligand is greater than 95% as determined by SEC-HPLC.