Cynomolgus ACE2/ACEH Protein (ACE-CM401)
Cynomolgus ACE2/ACEH Protein (ACE-CM401)
Cynomolgus ACE2/ACEH Protein (ACE-CM401)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus ACE2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for SARS-COV-2 Spike RBD, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln18-Val739
Catalog #ACE-CM401
Regular price $297.00
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Product Description

Recombinant Cynomolgus ACE2/ACEH Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln18-Val739.

Product Background

ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

ACE2/ACEH

Synonyms

ACE-2; ACEH; ACE2

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Gln18-Val739

Molecular Weight

The protein has a predicted MW of 86.5 kDa. Due to glycosylation, the protein migrates to 95-110 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Cynomolgus ACE2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for SARS-COV-2 Spike RBD, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus ACE2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for SARS-COV-2 Spike RBD, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA. Immobilized Cynomolgus ACE2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for SARS-COV-2 Spike RBD, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA.
Cynomolgus ACE2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus ACE2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus ACE2 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus ACE2 is greater than 95% as determined by SEC-HPLC.

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