Cynomolgus ADAM9 Protein (ADM-CM109)

Express System: HEK293
Product Tag: C-His
Purity: > 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Cynomolgus ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 0.8ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH₂. The specific activity is > 5.0 pmol/min/ug.
Amino Acid Range: Ala206-Gly698

Catalog #ADM-CM109

Price

$346⁵⁰

Size

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Cynomolgus ADAM9 Protein (ADM-CM109) Summary

Product Description	Recombinant Cynomolgus ADAM9 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala206-Gly698.
Product Background	A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS.

Protein	ADAM9
Synonyms	ADAM 9; Meltrin-gamma; Mdc9; Mltng; Adam9; Kiaa0021; AU020942; MDC9; mKIAA0021; CORD9; MCMP; MLTNG
Accession	A0A2K5X4X8
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ala206-Gly698
Molecular Weight	The protein has a predicted MW of 54.25 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 0.8ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH₂. The specific activity is > 5.0 pmol/min/ug.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 50mM Tris, 500mM NaCl, 0.005% Brij-35, 20% Glycerol (pH 8.5).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 0.8ng/ml determined by ELISA.
	Immobilized Cynomolgus ADAM9, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Izeltabart, hFc Tag with the EC50 of 1.1ng/ml determined by ELISA.
	Cynomolgus ADAM9 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
	The purity of Cynomolgus ADAM9 is greater than 90% as determined by SEC-HPLC.