Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein (ANG-CM103)
Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein (ANG-CM103)
Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein (ANG-CM103)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus ANGPTL3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Ser17-Glu460
Catalog #ANG-CM103
Regular price $315.00
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Product Description

Recombinant Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser17-Glu460.

Product Background

ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake.

Product Category

Recombinant Protein / Antibody discovery

Protein

ANGPTL3/Angiopoietin-like 3

Synonyms

ANGPTL3; ANGPT5; ANG-5; Angiopoietin-5; FHBL2; ANL3; Angiopoietin-5; Angiopoietin-like Protein 3

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Ser17-Glu460

Molecular Weight

The protein has a predicted MW of 52.86 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Cynomolgus ANGPTL3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus ANGPTL3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA. Immobilized Cynomolgus ANGPTL3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 9.0ng/ml determined by ELISA.
Cynomolgus ANGPTL3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus ANGPTL3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus ANGPTL3 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus ANGPTL3 is greater than 95% as determined by SEC-HPLC.

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