Name: Cynomolgus B7-H6/NCR3LG1 Protein (BH7-CM176)
Brand: KactusBio
SKU: BH7-CM176-100UG
Price: 270.0 USD
Availability: InStock

Cynomolgus B7-H6/NCR3LG1 Protein (BH7-CM176)

Human NKp30, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus B7-H6, His Tag with an affinity constant of 0.662 uM as determined in SPR assay (Biacore T200).

Cynomolgus B7-H6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus B7-H6 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: The affinity constant of 0.662 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Asp25-Asp259

Catalog #BH7-CM176

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus B7-H6/NCR3LG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp25-Asp259.
Product Background	B7-H6 is a glycosylated member of the B7 family of immune co‑stimulatory proteins, which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7-H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	B7-H6/NCR3LG1
Synonyms	B7H6; B7-H6; DKFZp686I21167; DKFZp686O24166; NCR3LG1; B7 Homolog 6
Accession	XP_005578557.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Asp25-Asp259
Molecular Weight	The protein has a predicted MW of 27.6 kDa. Due to glycosylation, the protein migrates to 40-52 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.662 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human NKp30, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus B7-H6, His Tag with an affinity constant of 0.662 uM as determined in SPR assay (Biacore T200).
	Cynomolgus B7-H6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus B7-H6 is greater than 95% as determined by SEC-HPLC.