Name: Cynomolgus B7-H7/HHLA2 Protein (BH7-CM177)
Brand: KactusBio
SKU: BH7-CM177-100UG
Price: 270.0 USD
Availability: InStock

Cynomolgus B7-H7/HHLA2 Protein (BH7-CM177)

Cynomolgus B7-H7, His Tag captured on CM5 Chip via anti-his antibody can bind Human CD28H, hFc Tag with an affinity constant of 7.86 nM as determined in SPR assay (Biacore T200).

Cynomolgus B7-H7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus B7-H7 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 7.86 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ile21-Asn345

Catalog #BH7-CM177

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus B7-H7/HHLA2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile21-Asn345.
Product Background	B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	B7-H7/HHLA2
Synonyms	B7H7; B7-H7; HHLA2; B7 Homolog 7
Accession	XP_005548285.2
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ile21-Asn345
Molecular Weight	The protein has a predicted MW of 38.31 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 7.86 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus B7-H7, His Tag captured on CM5 Chip via anti-his antibody can bind Human CD28H, hFc Tag with an affinity constant of 7.86 nM as determined in SPR assay (Biacore T200).
	Cynomolgus B7-H7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus B7-H7 is greater than 95% as determined by SEC-HPLC.